IL-2 (Interleukin 2)
- Animal-derived product free
- High Activity
- Authentic Glycosylation
- Lyophilized and Carrier Free (CF)
Xeno-free IL-2HuXp is an O-glycosylated, four alpha -helix bundle cytokine. It is expressed by gamma T cells, CD4+ and CD8+ T cells, eosinophils, B cells, and dendritic cells. IL-2 has potent stimulatory activity for antigen-activated T cells. It is a monomeric glycoprotein with an apparent molecular mass of 15 kDa. This cytokine is produced in a human cell expression system with serum-free, chemically defined media. Production in human 293 cells offers authentic glycosylation, which contributes to stability in cell growth media.
- Species: Human
- Expression: HEK293 Cell Expressed
- Activity: Typically ≤5 ng/mL EC50
- Purity: >95%
- Endotoxin: <1 EU/µg
- Molecular Mass: 15 kDa, monomer, glycosylated
- Formulation: 1x PBS
The protein was resolved by SDS- polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue.
The activity was determined by the dose- dependent stimulation of the proliferation of mouse CTLL-2 cells (mouse cytotoxic T cell line).
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA).
Synonyms: T-cell growth factor (TCGF), Aldesleukin IL2, IL 2, Tcell growth factor (TCGF), T cell growth factor (TCGF)