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IL-8 (Interleukin-8)
Product Description:
IL-8 is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is secreted by monocytes and endothelial cells. IL-8 chemoattracts and activates neutrophils. Recombinant Human IL-8 (monocyte-derived) is an 8.4 kDa protein containing 72 amino acid residues.
Technical Specifications:
- Species: Human
- Expression: E. coli Cell Expressed
- Purity: >98%
- Endotoxin: <1.0 EU/μg
- Molecular Mass: 8.4 kDa
- Country of Origin: USA
Purity Confirmation:
This was determined by SDS-PAGE gel and HPLC analysis.
Activity Assay:
Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10.0-100.0 ng/ml.
AA Sequence:
SAKELRCQCI | KTYSKPFHPK | FIKELRVIES |
GPHCANTEII | VKLSDGRELC | LDPKENWVQR |
VVEKFLKRAE | NS |
Reconstitution Buffer:
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex.
Storage:
This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% HSA) and store in working aliquots at -20°C to -80°C.
Cat #: | Size | Price |
HZ-7074 | 5 µg | $82 |
HZ-7075 | 25 µg | $201 |
HZ-7076 | 100 µg | $618 |
HZ-7115 | 250 µg | $1,082 |
HZ-7077 | 500 µg | $1,854 |
HZ-7078 | 1000 µg | $3,090 |