Products : Recombinant Human BMP-2

Products > Product Cytokines > BMP-2

Recombinant Human BMP-2  (Bone Morphogenetic Protein 2)

Product Description:

  • Endotoxin-free
  • Animal-derived product free
  • Available in Bulk
  • Lyophilized and Carrier Free (CF)
  • Glycosylated disulfide–linked homodimer

Xeno-free Recombinant Human BMP-2HuXp is expressed from human 293 cells as a disulfide linked homodimeric glycoprotein with an apparent molecular mass of 28 kDa. This cytokine is produced in a serum-free, chemically defined media. Production in human 293 cells offers authentic glycosylation, contributing to stability in cell growth media and other applications. BMPs (Bone Morphogenetic Proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite.

Technical Specifications:

  • Species: Human
  • Expression: HEK293 Cell Expressed
  • Activity: Typically ≤ 60 ng/mL EC50
  • Purity: >95%
  • Endotoxin: <1 EU/µg
  • Molecular Mass: 28 kDa, homodimer, glycosylated
  • Formulation: 2x PBS + 6% Ethanol

Purity Confirmation:

The protein was resolved by SDS- polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue.

Activity Assay:

The activity was determined by the dose dependent induction of alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line).

Reconstitution Buffer:

Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 4 mM HCl containing 0.1% endotoxin-free recombinant human serum albumin (HSA).

Recombinant Human BMP-2 Graph

Synonyms: BMP-2A BMP-2, BMP 2, BMP2
Cat #: Size Price
HZ-1128 10 µg $226
HZ-1129 100 µg $1,591
HZ-1130 1000 µg $6,610

Human Cell Expressed

Animal Component-Free, Xeno-Free Production