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IL-5 (Interleukin-5)
Product Description:
IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant Human IL-5 is a 26.5 kDa disulfide-linked homodimeric protein containing two 116 amino acid chains.
Technical Specifications:
- Species: Human
- Expression: E. coli Cell Expressed
- Activity: Typically ≤0.15 ng/mL ED50
- Purity: >98%
- Endotoxin: <1.0 EU/μg
- Molecular Mass: 26.5 kDa, homodimeric
- Formulation: 20mM Sodium Phosphate, pH 7.5
- Country of Origin: USA
Purity Confirmation:
This was determined by SDS-PAGE gel and HPLC analysis.
Activity Assay:
Determined by its ability to stimulate the proliferation of human TF-1 cells.
AA Sequence:
GPETLCGAEL | VDALQFVCGD | RGFYFNKPTG |
YGSSSRRAPQ | TGIVDECCFR | SCDLRRLEMY |
CAPLKPAKSA |
Reconstitution Buffer:
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex.
Storage:
This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% HSA) and store in working aliquots at -20°C to -80°C.
Cat #: | Size | Price |
HZ-7068 | 2 µg | $82 |
HZ-7069 | 10 µg | $201 |
HZ-7070 | 100 µg | $886 |
HZ-7071 | 250 µg | $1,550 |
HZ-7072 | 500 µg | $2,657 |
HZ-7073 | 1000 µg | $4,429 |