Prolactin is a neuroendocrine hormone secreted by the pituitary gland. Its primary function is to promote and maintain lactation during pregnancy and suckling. In addition, prolactin plays an immunoegulatory role by stimulating the activities of ornithine decarboxylase and protein kinase C, which are important for the proliferation, differentiation, and function of lymphocytes. Recombinant Human Prolactin is a 23.0 kDa globular protein containing 200 amino acid residues.
- Species: Human
- Expression: E. coli Cell Expressed
- Purity: ≥98%
- Endotoxin: <1.0 EU/μg
- Molecular Mass: 23.0 kDa
- Formulation: 10 mM Sodium Phosphate, pH 8.0 + 50 mM NaCl
- Country of Origin: USA
This was determined by SDS-PAGE gel and HPLC analysis.
Determined by its ability to induce proliferation of rat Nb2- 11 cells in the concentration range of 0.1-1.0 ng/ml.
Centrifuge the vial prior to opening. Reconstitute in Sodium Phosphate, pH 8.0, to a concentration of 0.1-1.0 mg/ml. Do not vortex.
For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% HSA) and store in working aliquots at -20°C to -80°C.