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IL-5 (Interleukin-5)

Product Description:

IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant Human IL-5 is a 26.5 kDa disulfide-linked homodimeric protein containing two 116 amino acid chains.

Technical Specifications:

  • Species: Human
  • Expression: E. coli Cell Expressed
  • Activity: Typically ≤0.15 ng/mL ED50
  • Purity: >98%
  • Endotoxin: <1.0 EU/μg
  • Molecular Mass: 26.5 kDa, homodimeric
  • Formulation: 20mM Sodium Phosphate, pH 7.5
  • Country of Origin: USA

Purity Confirmation:

This was determined by SDS-PAGE gel and HPLC analysis.

Activity Assay:

Determined by its ability to stimulate the proliferation of human TF-1 cells.

AA Sequence:

GPETLCGAEL VDALQFVCGD RGFYFNKPTG
YGSSSRRAPQ TGIVDECCFR SCDLRRLEMY
CAPLKPAKSA

Reconstitution Buffer:

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex.

Storage:

This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% HSA) and store in working aliquots at -20°C to -80°C.

Cat #: Size Price
HZ-7068 2 µg $82
HZ-7069 10 µg $201
HZ-7070 100 µg $886
HZ-7071 250 µg $1,550
HZ-7072 500 µg $2,657
HZ-7073 1000 µg $4,429

XKine™ proteins are expressed in several expression systems

If your protein is not listed please inquire. Good possibility we might have it.

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