Products

Products > XKine Products > IL-17E

IL-17E (Interleukin-17E)

Product Description:

IL-17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulates secretion of IL-8, and induces activation of the transcription factor NF-κB in cells that express the IL-17BR receptor. Recombinant Human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 146 amino acid polypeptide chains.

Technical Specifications:

  • Species: Human
  • Expression: E. coli Cell Expressed
  • Purity: ≥98%
  • Endotoxin: <1.0 EU/μg
  • Molecular Mass: 33.8 kDa
  • Country of Origin: USA

Purity Confirmation:

This was determined by SDS-PAGE gel and HPLC analysis.

Activity Assay:

Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10.0-100.0 ng/ml. Results will vary with PBMC donors.

AA Sequence:

MYSHWPSCCP SKGQDTSEEL LRWSTVPVPP
LEPARPNRHP ESCRASEDGP LNSRAISPWR
YELDRDLNRL PQDLYHARCL CPHCVSLQTG
SHMDPRGNSE LLYHNQTVFY RRPCHGEKGT
HKGYCLERRL YRVSLACVCV RPRVMG

Reconstitution Buffer:

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex.

Storage:

This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% HSA) and store in working aliquots at -20°C to -80°C.

Cat #: Size Price
HZ-7120 5 µg $82
HZ-7121 25 µg $201

XKine™ proteins are expressed in several expression systems

If your protein is not listed please inquire. Good possibility we might have it.

Click to Inquire