FGF-10 (Fibroblast Growth Factor-10)
FGF-10 is a heparin-binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-10 is most related to KGF/FGF-7, and is expressed during the development and, preferentially, in adult lungs. It signals through the FGFR 2b.
- Species: Human
- Expression: E. coli Cell Expressed
- Activity: Typically ≤0.5 ng/ml ED50
- Purity: ≥95%
- Endotoxin: <1.0 EU/μg
- Molecular Mass: 19.3 kDa
- Formulation: 5mM Sodium Phosphate pH 7.4 + 80 mM NaCl
- Country of Origin: USA
This was determined by SDS-PAGE gel and HPLC analysis.
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
Centrifuge the vial prior to opening. 5mM Sodium Phosphate, pH 7.4 to a concentration of 0.1-1.0 mg/ml. Do not vortex.
For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% HSA) and store in working aliquots at -20°C to -80°C.