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FGF-10 (Fibroblast Growth Factor-10)

 Product Description:

FGF-10 is a heparin-binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-10 is most related to KGF/FGF-7, and is expressed during the development and, preferentially, in adult lungs. It signals through the FGFR 2b.

Technical Specifications:

  • Species: Human
  • Expression: E. coli Cell Expressed
  • Activity: Typically ≤0.5 ng/ml ED50
  • Purity: ≥95%
  • Endotoxin: <1.0 EU/μg
  • Molecular Mass: 19.3 kDa
  • Formulation: 5mM Sodium Phosphate pH 7.4 + 80 mM NaCl
  • Country of Origin: USA

Purity Confirmation:

This was determined by SDS-PAGE gel and HPLC analysis.

Activity Assay:

The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.

AA Sequence:

MLGQDMVSPE ATNSSSSSFS SPSSAGRHVR
SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV
SGTKKENCPY SILEITSVEI GVVAVKAINS
NYYLAMNKKG KLYGSKEFNN DCKLKERIEE
NGYNTYASFN WQHNGRQMYV ALNGKGAPRR
GQKTRRKNTS AHFLPMVVHS

Reconstitution Buffer:

Centrifuge the vial prior to opening. 5mM Sodium Phosphate, pH 7.4 to a concentration of 0.1-1.0 mg/ml. Do not vortex.

Storage:

For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% HSA) and store in working aliquots at -20°C to -80°C.

Cat #: Size Price
HZ-7318 5 µg $82
HZ-7158 25 µg $195
HZ-7163 100 µg $600
HZ-7138 500 µg $1,800
HZ-7359 1000 µg $3,000

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