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Products > Product CytokinesTPO

TPO  (Thrombopoietin)

Product Description:

  • Endotoxin-free
  • Animal-derived product free
  • Lyophilized and Carrier Free (CF)
  • Authentic Glycosylation
  • Available in Bulk

Xeno-free TPOHuXp is expressed from human 293 cells as a monomeric glycoprotein with an apparent molecular mass of 80 to 85 kDa. This cytokine is produced in a serum-free, chemically defined media. Production in human 293 cells offers authentic glycosylation, contributing to stability in cell growth media and other applications. C- terminal domain glycosylation is thought to be important for the secretion of TPO from cells and for survival of TPO in the circulation.

Technical Specifications:

  • Species: Human
  • Expression: HEK293 Cell Expressed
  • Activity: Typically ≤ 5 ng/mL EC50
  • Purity: >95%
  • Endotoxin: < 1 EU/µg
  • Molecular Mass: 80 to 85 kDa, monomer, glycosylated.
  • Formulation: 1x PBS

Purity Confirmation:

The protein was resolved by SDS- polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue.

Activity Assay:

The activity was determined by the dose- dependent stimulation of the proliferation of MO7e cells.

Reconstitution Buffer:

Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA).

Synonyms: Thrombopoietin, Megakaryocyte colony-stimulating factor, c-MPL Ligand, MGDF cMPL Ligand, c MPL Ligand,

Cat #: Size Price
HZ-1248 10 µg $266
HZ-1227 100 µg $2,255
HZ-1249 1000 µg $4,047

Human Cell Expressed

Animal Component-Free, Xeno-Free Production