TGF beta 3 (Transforming Growth Factor beta 3)
- Animal-derived product free
- Available in Bulk
- Lyophilized and Carrier Free (CF)
- High Activity
Xeno-free TGF beta 3HuXp is expressed from human 293 cells as a mature disulfide-linked homodimer with apparent molecular mass of 25 kDa. This cytokine is produced in a human cell expression system with serum-free, chemically defined media. The cytokine is greater than 95% pure.
- Species: Human
- Expression: HEK293 Cell Expressed
- Activity: Typically ≤0.5 ng/mL EC50
- Purity: >95%
- Endotoxin: <1 EU/µg
- Molecular Mass: 25 kDa, homodimer, non-glycosylated
- Formulation: 50 mM NaOAc pH 3.7
The protein was resolved by SDS- polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue.
The activity was determined by the dose- dependent inhibition of IL-4 induced proliferation of mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2).
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 4 mM HCl containing 0.1% endotoxin-free recombinant human serum albumin (HSA).
Synonyms: Transforming Growth Factor-β2, Glioblastoma-derived T cell suppressor factor, BSC-1, Cetermin, Polyergin TGFbeta3, Transforming Growth Factorβ2, Transforming Growth Factor β2, BSC1, BSC 1