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Products > Product Cytokines > TGF beta 1

TGF beta 1  (Transforming Growth Factor Beta 1)

Product Description:

  • Endotoxin-free
  • Animal-derived product free
  • Available in Bulk
  • Lyophilized and Carrier Free (CF)

Xeno-free TGF beta 1HuXp is expressed from human 293 cells as a mature disulfide-linked homodimer with an apparent molecular mass of 25 kDa. Tests indicate that TGF beta 1 is as efficient at inducing IL-17 expression in Th17 cells, as cytokine purified from human platelets. This product is produced in a human cell expression system with serum-free, chemically defined media.

Technical Specifications:

  • Species: Human
  • Expression: HEK293 Cell Expressed
  • Activity: Typically ≤0.5 ng/mL EC50
  • Purity: >95%
  • Endotoxin: <1 EU/µg
  • Molecular Mass: 25 kDa, homodimer, nonglycosylated
  • Formulation: 50 mM NaOAc pH 4.5

Purity Confirmation:

The protein was resolved by SDS- polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue.

Activity Assay:

The activity was determined by the dose dependent inhibition of IL-4 induced proliferation of mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2)..

Reconstitution Buffer:

Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 4 mM HCl containing 0.1% endotoxin-free recombinant human serum albumin (HSA).

Synonyms: Transforming Growth Factor-&beta;1, Differentiation inhibiting factor, Cartilage-inducing factor Transforming Growth Factor&beta;1, Transforming Growth Factor- beta;1

Cat #: Size Price
HZ-1011 5 µg $226
HZ-1131 100 µg $2,334
HZ-1087 1000 µg $9,135

Human Cell Expressed

Animal Component-Free, Xeno-Free Production