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Products > Product Cytokines > LEFTY-1

LEFTY-1  (Recombinant Human)

Product Description:

  • Endotoxin-free
  • Animal-derived product free
  • Lyophilized and Carrier Free (CF
  • High Activity
  • Authentic Glycosylation

Xeno-free LEFTY-1HuXp is expressed in human 293 cells as a monomeric glycoprotein with an apparent molecular mass of 38 kDa. This cytokine is produced in a human cell expression system with serum-free, chemically defined media. Production in human 293 cells offers authentic glycosylation, contributing to stability in cell growth media.

Technical Specifications:

  • Species: Human
  • Expression: HEK293 Cell Expressed
  • Activity: Typically ≤40 ng/mL EC50
  • Purity: >95%
  • Endotoxin: <1 EU/μg
  • Molecular Mass: 38 kDa, monomer, glycosylated
  • Formulation: 10 mM Tris-HCl pH 7.4 + 50 mM NaCl + 0.5% CHAPS

Purity Confirmation:

The protein was resolved by SDS-polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue.

Activity Assay:

The activity was determined by dose dependent ability to inhibit BMP-4 (6.5 ng/mL) induction of alkaline phosphatase production in the MC-3T3-E1 cell line (Mouse chondrogenic cell line).

Reconstitution Buffer:

Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile water containing 0.1% endotoxin-free recombinant human serum albumin (HSA).

Synonyms: LEFTY1, LEFTY 1

Cat #: Size Price
HZ-1109 10 µg $313
HZ-1190 100 µg $2,255
HZ-1191 1000 µg $10,986

Human Cell Expressed

Animal Component-Free, Xeno-Free Production