IL-3 (lnterleukin 3)
- Animal-derived product free
- Lyophilized and Carrier Free (CF)
- Authentic Glycosylation
Xeno-free IL-3HuXp expressed in human 293 cells is a glycosylated monomer with an apparent molecular mass of 17 to 40 kDa. This broad molecular mass is attributable to glycosylation, which is absent when this cytokine is expressed in E. coli. A hematopoietic growth factor, IL-3 promotes the survival, differentiation, and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, basophil, erythroid, eosinophil, and mast cell lineages. This cytokine can also improve the natural response to disease as part of the body’s immune system.
- Species: Human
- Expression: HEK293 Cell Expressed
- Activity: Typically ≤2 ng/mL EC50
- Purity: >95%
- Endotoxin: <1 EU/µg
- Molecular Mass: 17 to 40 kDa, monomer, glycosylated
- Formulation: 1xPBS
The protein was resolved by SDS- polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue.
The activity was determined by the dose dependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile I xPBS.
Synonyms: MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor IL3, IL 3, Multi CSF, MultiCSF, Pcell stimulation factor, P cell stimulation factor