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Products > Product Cytokines > IL-23

IL-23  (Interleukin 23)

Product Description:

  • Endotoxin-free
  • Animal-derived product free
  • Available in Bulk
  • Lyophilized and Carrier Free (CF)
  • Expressed as disulfide-linked heterodimer

Xeno-free IL-23HuXp is expressed in human 293 cells as a heterodimeric glycoprotein composed of two disulfide-linked subunits (p40 cystine linked to p19). IL-23 has been shown to enhance proliferation of memory T cells. It also stimulates the production of IFN-gamma in NK cells, induces IL-17 production, and drives Th17 mediated responses. Furthermore, it is known that IL-23 takes a vital part in the inflammation process and that it is associated with auto immune diseases.

Technical Specifications:

  • Species: Human
  • Expression: HEK293 Cell Expressed
  • Activity: Typically ≤ 30 ng/mL EC50
  • Purity: >95%
  • Endotoxin: <1 EU/µg
  • Molecular Mass: 55 kDa, heterodimer, glycosylated
  • Formulation: 1x PBS

Purity Confirmation:

The protein was resolved by SDS- polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue.

Activity Assay:

The activity was determined by the dose- dependent secretion of IL-17 in response to IL-23 using murine splenocytes.

Reconstitution Buffer:

Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA).

Synonyms: IL 23, IL23
Cat #: Size Price
HZ-1254 10 µg $289
HZ-1261 100 µg $1,735
HZ-1262 1000 µg $11,332

Human Cell Expressed

Animal Component-Free, Xeno-Free Production