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Products > Product Cytokines > IL-1 Beta

IL-1 beta  (Interleukin 1 beta)

Product Description:

  • Endotoxin-free
  • Animal-derived product free
  • Available in Bulk
  • Authentic Glycosylation
  • Lyophilized and Carrier Free (CF)

Xeno-free IL-1 betaHuXp expressed in human 293 cells has a very high activity with a typical EC50 of ≤0.1 ng/mL using a bioassay to measure stimulation of the proliferation of mouse D10S cells. In comparison with the E. coli expressed protein, IL-1 beta is 50% more potent promoting human CD4+ T cell differentiation into Th17 cells. This cytokine is important for inflammatory responses. It is also involved in a variety of cellular activities which includes cell differentiation, proliferation, and apoptosis. It is produced in a serum-free, chemically defined media.

Technical Specifications:

  • Species: Human
  • Expression: HEK293 Cell Expressed
  • Activity: Typically ≤0.1 ng/mL EC50
  • Purity: >95%
  • Endotoxin: <1 EU/µg
  • Molecular Mass: 18 and 25 kDa, monomer, glycosylated
  • Formulation: 1x PBS

Purity Confirmation:

The protein was resolved by SDS- polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue.

Activity Assay:

The activity was determined by the dose- dependent stimulation of the proliferation of mouse D10S cells.

Reconstitution Buffer:

Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA).

Synonyms: Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF) Lymphocyte activating factor (LAF)

Cat #: Size Price
HZ-1164 10 µg $226
HZ-1165 100 µg $1,167
HZ-1166 1000 µg $4,510

Human Cell Expressed

Animal Component-Free, Xeno-Free Production