BMP-7 (Recombinant Human)
- Animal-derived product free
- Available in Bulk
- Lyophilized and Carrier Free (CF)
- Glycosylated disulfide–linked homodimer
Xeno-free BMP-7 is expressed in human 293 cells as a disulfide linked homodimeric glycoprotein with an apparent molecular mass of 29 kDa. This cytokine is produced in a serum-free, chemically defined media. Recombinant Human BMP-7 is a homodimeric glycoprotein consisting of two 117 amino acid subunits, which correspond to amino acid residues 315 to 431 of the full-length BMP-7 precursor. The protein encoded by this gene is a member of the TGF-beta superfamily. Like other members of the Bone Morphogenetic Protein family of proteins, it plays a key role in the transformation of mesenchymal cells into bone and cartilage.
- Species: Human
- Expression: HEK293 Cell Expressed
- Activity: Typically ≤ 100 ng/mL EC50
- Purity: >95%
- Endotoxin: <1 EU/µg
- Molecular Mass: 29 kDa, homodimer, glycosylated
- Formulation: 2x PBS + 20% Ethanol
The protein was resolved by SDS- polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue.
The activity was determined by the dose dependent induction of alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line).
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile water containing 0.1% endotoxin-free recombinant human serum albumin (HSA).
Synonyms: OP-1 BMP 7, BMP7, OP 1, OP7